Is It Safe to Use Stevia instead of sugar

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It is precisely this compound steviol that for many years called Science-Based Ketox Review attention to toxicologists. In studies with bacteria and in cell-cultures it was demonstrated that this compound is genotoxic (i.e. is capable of changing the genetic information). However, more recent studies with mice, rats and hamsters, indicated that it requires relatively high concentrations of steviol to cause any considerable damage to the DNA, the molecule of life containing all our genetic information.

Browsing toxicological databases, there are hundreds of publications discussing potential adverse health effects of stevia extract, but the results are not very consistent. In particular, the effects on fertility and the potential carcinogenicity of Steviosides were subject of controversy in the scientific world. It was a study published in 1968 by Professor Joseph Kuc Purdue University in Indiana, USA, which initiated a controversial discussion about stevia and fertility. Prof. Kuc detected a clear contraceptive effect on female rats that were administered high doses of stevia. The fertility rates of the rats dropped by up to 79 percent.

While the outcome of this study was not confirmed by other scientific groups, a study published in 1999 by Prof. Melis of the University of Sao Paulo also reported a reduction of sperm quantity in male rats after applying high doses of Stevia glycosides. Concerns of carcinogenicity or mutagenicity were not confirmed in the vast majority of the toxicological studies.

Although adverse health effects of Stevia never really have been tested in humans directly, the authorities in the United States, Canada and the European Union considered Stevia extracts not to be safe in the application as a tabletop sweetener due to the lack of long-term toxicological studies. In contrast, authorities in other countries like Japan, China, Australia, New Zealand, Brazil and Mexico have a different point of view and accepted the use of extracts of Stevia as a natural sweetener. In several other countries, in particular in Latin American and Asia, Stevia and its extracts are available with and unverified regulatory status. In Japan, Stevia extracts are already commercially available since 1971 as tabletop sweetener and there are no reports about health problems associated with this product.

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