Manly Glasses Are Less Fashionable? Never

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Glenn Beck's health problem, macular Vision 20/20 Protocol Ebook Review  dystrophy, is not to be confused with the much more common cause of blindness in the United States, macular degeneration. It is a rare problem. In my 25 years on the front lines of clinical nutrition I have never seen a single person with the issue, while I have helped many with macular degeneration. Since Mr. Beck is unlikely to understand the technical nature of his problem I looked into it for him.

His problem involves his cornea, which is the major refractive structure of the outer part of the eye. This structure must hold water to provide cushioning to protect the eye while at the same time allowing light through in an unobstructed manner. A key layer of the cornea, called the corneal stroma, is developing clouds that block his vision. Scientists have identified the gene weakness involved, and the problem is considered essentially untreatable and progressive. Or is it?

The first clue that his diagnosis is atypical is that true macular dystrophy shows up early in life, as the eye structure is simply unable to maintain its integrity. So why does Mr. Beck all of a sudden have this problem show up at his age? Genes are pliable, never fixed in concrete. Gene-related problems that pop up at unexpected times tend to mean that other health problems have enabled a genetic weak spot to manifest as a medical problem. This is actually good news for Mr. Beck, as it means he has a much higher chance of keeping that weakness in check, possibly reversing the current situation or preventing it from worsening. Yes, there is a glimmer of hope.

The next step is to understand the nature of the problem. Scientists have done a fairly good job of defining how the problem presents itself. The corneal stroma is made up of something called keratin sulfate, a type of proteoglycan that is a mix of carbohydrate and protein that forms the tissue matrix of the cornea. In this case, it is highly sulfated enabling a negative charge on the structure so as to be able to hold water as cushioning in case your eye bumps into something. In macular dystrophy there is a genetic inability to synthesize keratin sulfate or the keratin sulfate that is produced is abnormal in structural integrity.

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