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[Jamie Jones]

Bone resorption is increased after running, with no change in bone formation. Feeding during cheap runescape gold exercise might attenuate this increase, preventing associated problems for bone. This study investigated the immediate and short term bone metabolic responses to carbohydrate (CHO) feeding during treadmill running. On day 4 of each trial, participants completed a 120 min treadmill run at 70% of maximal oxygen consumption (VO2 max). Blood was taken at baseline (BASE), immediately after exercise (EE), after 60 (R1) and 120 (R2) min of recovery, and on three follow up days (FU1 FU3). Markers of bone resorption [COOH terminal telopeptide region of collagen type 1 ( CTX)] and formation [NH2 terminal propeptides of procollagen type 1 (P1NP)] were measured, along with osteocalcin (OC), parathyroid hormone (PTH), albumin adjusted calcium (ACa), phosphate, glucagon like peptide 2 (GLP 2), interleukin 6 (IL 6), insulin, cortisol, leptin, and osteoprotogerin (OPG). Area under the curve was calculated in terms of the immediate (BASE, EE, R1, and R2) and short term (BASE, FU1, FU2, and FU3) responses to exercise. CTX, P1NP, and IL 6 responses to exercise were significantly lower in the immediate postexercise period with CHO feeding compared with PBO ( CTX: P=0.028; P1NP: P=0.021; IL 6: P=0.036), although there was no difference in the short term response ( CTX: P=0.856; P1NP: P=0.721; IL 6: P=0.327). No other variable was significantly affected by CHO feeding during exercise. We conclude that CHO feeding during exercise attenuated the CTX and P1NP responses in the hours but not days following exercise, indicating an acute effect of CHO feeding on bone turnover.

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