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1 Sep 2006 Source: OECD Guidelines for the Testing of Chemicals, Volume 1, The sister chromatid exchange (SCE) assay is a short?term test for the Following the OECD Council decision, the Test Guideline 479 'Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells' was deleted Following the OECD Council decision, the Test Guideline 479 'Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells' was deleted 23 Oct 1986 Users of this Test Guideline should consult the Preface, The sister chromatid exchange (SCE) assay is a short-term test for the detection of. INTRODUCTION This guideline is one of a series of test guidelines that have been by the Organization for Economic Cooperation and Development (OECD). The sister chromatid exchange (SCE) assay detects the ability of a chemical to21 Jul 1997 this guideline is not designed to measure numerical aberrations and is not .. Chromosome aberration and sister chromatid exchanges in. The study design follows the current OECD Guideline for Testing of Chemicals – 479, Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in This Introduction to the Test Guidelines (TG) on genetic toxicology is intended to provide 479 In vitro sister chromatid exchange assay in mammalian cells. Genetic toxicology Guidance Document Aug 31, 2015. 1. Guidance Document In addition, TG 479 (in vitro sister chromatid exchange test in. 67 mammalian 29 Oct 2012 The OECD Guidelines for the Testing of Chemicals are periodically reviewed in .. Chromosomal aberration and sister chromatid exchanges in.