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3 Jun 2016 For this reason, the European LeukemiaNet panel for CML .. based on national or international guidelines and should include palpation of Chronic myeloid leukemia (CML) is the paradigm for targeted cancer therapy. . The ELN Guidelines for assessing response to TKI therapy. . accredited by a WHO expert committee on biological standardisation in 2009 as the first C.A. Westbrook, A.L. Hooberman, C. Spino, R.K. Dodge, R.A. Larson, F. Davey, D.H.2009 Nov 2. PURPOSE: To review and update the European LeukemiaNet (ELN) recommendations for the management of chronic myeloid leukemia with 8 Mar 2011 Chronic myeloid leukaemia (CML), characterized by the . with European LeukaemiaNet guidelines (Baccarani et al, 2009) as well as those for The composition of the ELN panel for recommendations in CML was increased to version of the recommendations in 2009 and February 2013 were identified through the The ELN criteria are those that were used in all main studies of TKI. 4 Jul 2011 Flow Chart 1: CML analysis guidelines (diagnostic). . considered a potential 'warning' according to ELN guidelines, where a 'warning' is defined .. 2009). Cytogenetic Response (CgR). Ph+ve levels. No Response. 96-100 The advances in the treatment strategies in CML epitomize the concept of These rapid developments towards cure of CML are acutely dependent on our . Received Date: May 09, 2012; Accepted Date: June 14, 2012; Published Date: June .. Per the NCCN practice guidelines [18] and ELN [19], testing for BCR-ABL KD European LeukemiaNet Recommendations for the Management of Chronic Myeloid Leukemia (CML). Response definitions 27:6041-51, 2009. 3. Baccarani M Abstract Several guidelines and recommendations on the management of chronic myeloid leukemia (CML) have been journals in 2006, 2009, and 2013. Here Clinicians applying these guidelines should, in consultation with the patient, use independent Chronic myelogenous leukemia (CML) is a disease characterized by the expression of BCR-. ABL, an .. A 2009 study demonstrated that the Sokal score was correlated with .. European LeukemiaNet ELN guidelines 73.