Chinese Association of Idaho State University (CAISU)
FL, Bray GA. Regional fat loss from the thigh in obese women after adrenergic modulation. Clin Ther. 1987; 9(6):663-9. Twenty-eight obese women were placed on a calorie-restricted diet, and treatments containing forskolin were applied to one thigh
three to five times per week for four weeks, with the opposite thigh treated with placebo. The treated thighs lost significantly more girth after treatment, both by injection and by cream. No adverse reactions were attributable to either the cream or the injections. The researchers concluded that localized fat reduction could safely be accomplished.
Roure, R., et al., International Journal of Cosmetic Science, 2011, 22, 519-26, April 2011. To evaluate the effectiveness of topical products containing forskolin, three double-blind, randomized, placebo-controlled studies showed, after 4 weeks of twice-daily applications, significant reductions in size of abdomen, hips, waist and buttocks.
Shonteh Henderson, et al., Effects of Coleus Forskohlii Supplementation on Body Composition and Hematological Profiles in Mildly Overweight Women, Jour. Int'l Soc. Sports Nutrition, 2(2): 54-62, 2005. This study was conducted at the Exercise & Sport Nutrition Laboratory at Baylor University in Waco, TX. Twenty-three females supplemented their diet with Forskolin (250 mg of 10% CF extract) or a placebo two times a day for 12 weeks. The researchers concluded that Forskolin helped control weight gain in overweight females with apparently no clinically significant side effects.
Godard MP, et al. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obes Res. 2005; 13:1335-1343. In perhaps the strongest study to date, thirty obese men were studied for 12 weeks. Results showed a dramatic decrease in body and fat mass, and an increase in lean body mass and bone mass, among those taking Forskolin. These results were attributed to the free fatty acid release caused by increased cAMP produced by the Forskolin.